Piers Morgan stormed off the set of Good Morning Britain declaring he was "done" after he was criticised for "trashing" Meghan Markle and being reminded that the Duchess had "cut him off".
Morgan was challenged by co-presenter Alex Beresford for his "diabolical" response to Meghan and Harry's tell-all interview with Oprah Winfrey, which saw Morgan dub the pair "sickening, shameful and self-pitying", among many other insults.
"Who did you go to?" he said during the post-interview broadcast on Monday morning (UK time).
"What did they say to you? I'm sorry, I don't believe a word she said, Meghan Markle. I wouldn't believe it if she read me a weather report."
- CBS Presents Oprah with Meghan and Harry can be watched in full on ThreeNow.
Morgan's lengthy diatribe against the claims made by the Duchess of Sussex - including revelations that she had suffered suicidal thoughts and been refused help by the royal institution - prompted 41,000 complaints to Ofcom, Britain's broadcasting and communications regulator, and launched an investigation.
Beresford admonished Morgan for "continuing to trash" Meghan and Harry, but seemed to strike a nerve when he referred to Morgan's previous friendship with the Duchess.
"I understand you don't like Meghan Markle - you've made it so clear a number of times on this programme, a number of times," Beresford said.
"And I understand that you've got a personal relationship with Meghan Markle, or had one and she cut you off. She's entitled to cut you off if she wants to.
"Has she said anything about you since she cut you off? I don't think she has, yet you continue to trash her."
Morgan then stood up and declared "I'm done with this", before storming off the ITV set.
"Sorry, no, can't do this," he said on his way out.
Morgan has spoken about his former friendship with the Suits actress, declaring he had been "hurt" when Meghan "ghosted" him.
After his hasty exit, Morgan returned 10 minutes later to conduct an interview with Meghan's father Thomas Markle, but hours later announced it was announced he would be leaving his role on Good Morning Britain.
"Following discussions with ITV, Piers Morgan has decided now is the time to leave Good Morning Britain," the television network said in a statement.
Morgan has not made his own statement since the news but did share a gif of a ticking clock to his Twitter.