Tottenham Hotspur's home Europa Conference League game against Rennes on Thursday has been called off due to the number of coronavirus cases in the Spurs squad.
Coach Antonio Conte confirmed earlier that there had been 13 positive cases at Tottenham, eight players and five members of staff.
"We can confirm that our UEFA Europa Conference League Group G home fixture against Stade Rennais will not take place tomorrow after a number of positive COVID-19 cases at the club, the statement read," the club says.
"Discussions are ongoing with UEFA and we shall provide a further update on this fixture in due course.
"Additionally, the club has been advised to close the first team area of its training centre at this time, in the interests of the health and safety of players and staff."
It was unclear whether other Spurs games will be affected.
They are scheduled to play Brighton & Hove Albion in the Premier League this weekend, Leicester City on December 16 and Liverpool on December 19.
"The situation makes me very upset because the situation is serious," Conte told a news conference.
"It's contagious and there is a big infection. Now we are a bit scared because tomorrow we don't know what will happen.
"Every day, we are having more positives. This is not a good situation."
Reuters