The Blues have confirmed a "small number" of their playing squad have tested positive for COVID-19.
The news comes just hours before their round four clash with the Highlanders at North Harbour Stadium on Friday.
The game will still proceed as planned, albeit with some changes to the Blues match-day 23, which are yet to be announced.
The affected players are self-isolating and are under strict protocols in accordance with NZ Rugby's COVID-19 guidelines.
Three games - all involving Moana Pasifika - have already been postponed this season due to COVID-19 outbreaks, including Saturday's scheduled match against the Hurricanes.
On Friday, NZ Rugby announced Moana Pasifika will play mid-week games against the Blues and Chiefs as part of an adjusted schedule to make up the lost matches.
The newcomers will face the Blues on Tuesday, March 29 at Mt Smart Stadium, before playing them again four days later at Eden Park in round seven of the competition.
They'll make up their match against the Chiefs at FMG Stadium at Hamilton on Tuesday, April 12, then again at Mt Smart on April 16 in round nine.
In between, they will have a bye week in round eight to help reduce some of the impact of the quick turnaround between games.
The rescheduled matches also mean the Highlanders' round nine home match at Forsyth Barr Stadium in Dunedin - initially scheduled for Saturday, April 16 - will switch places with the Moana Pasifika v Chiefs match, which moves forward one day.
Join Newshub for live updates of the Blues v Highlanders Super Rugby Pacific clash from 7pm Friday.