Iranian emergency officials have confirmed a plane crash near Tehran, Iran has killed all those on board.
Ukraine Minister for Foreign Affairs Vadym Prystaiko confirmed 176 people were killed.
The nationalities of the victims are 82 from Iran, 63 from Canada, 11 from Ukraine - nine of which were flight crew members, 10 from Sweden, four from Afghanistan, three from Germany and three from the United Kingdom.
The flight departed at 6:12am (local time) on Wednesday from Imam Khomeini airport in Tehran and crashed about eight minutes later, according to flight tracking websites.
Aslani said the cause of the crash was a fire in the engine of the aircraft.
Rescuers are now trying to collect the dead, according to emergency official Pir Hossein Kulivand.
An investigation team was at the site of the crash in southwestern outskirts of Tehran, civil aviation spokesperson Reza Jafarzadeh said.
"After taking off from Imam Khomeini International Airport, it crashed between Parand and Shahriar," Jafarzadeh said.
"An investigation team from the national aviation department was dispatched to the location after the news was announced."
Flight data from the airport showed once the plane took off, it stopped sending data almost immediately afterward, according to website FlightRadar24. The flight was bound for Kyiv, Ukraine.
A photo later published by Iran's state-run IRNA news agency showed rescue officials in a farm field, with what appeared to be pieces of the aircraft laying nearby.
Boeing released a statement saying it is aware of media reports out of Iran and is gathering more information.
Early indications suggest the crash doesn't appear to be linked to Wednesday's missile strikes on bases in Iraq.