A 12-year-old boy from Oklahoma has died after attempting the "blackout challenge" circulating on the video-sharing app TikTok.
He is the latest child to die due to the challenge, which involves individuals filming themselves holding their breath or choking themselves until they lose consciousness.
Doctors warn the challenge, which limits oxygen to the brain, can cause seizures, brain damage and death.
Local media report the family members told police the incident was not a suicide, despite the boy being found with ligature marks on his neck.
"We would like to warn parents to stay involved with their children and take the time to look at what they are doing on social media," warned police officer Lieutenant Angelo Orefice.
"Social media is a very influential part of a child's life and should be heavily scrutinised by parents."
A 10-year-old girl from Italy was declared brain-dead after trying the challenge in January.
In April, the family of Joshua Haileyesus turned off his life-support after the 12-year-old from Colorado was left brain dead.
The trend also allegedly claimed the life of US teenager Nate Squires, his parents reportedly "wanting the world to know of the circumstances that surround [his] death to ensure that this does not happen to another family".
Following Haileyesus' death, TikTok said it has "no higher priority than protecting the safety" of its users.
"Content that promotes or glorifies dangerous behaviour is strictly prohibited and promptly removed to prevent it from becoming a trend on our platform."