Lizzo says she felt she needed to keep her love of Radiohead hidden when she was at school to avoid being bullied.
"It was a Black school, mostly Black and brown, Caribbean, I had Nigerian friends," Lizzo told Vanity Fair.
"They were all listening to what was on the radio: Usher, Destiny's Child, Ludacris, and I was into Radiohead's OK Computer.
"[I] kept it hidden, even when I was in a rock band, because I didn't want to be made fun of by my peers - they'd yell, 'White girl!'
"Also, I was wearing these flared bell-bottoms with embroidery down it - and they'd say: 'You look like a white girl, why do you want to look like a hippie?'
"I wanted to be accepted so bad; not fitting in really hurt."
The 'Truth Hurts' singer also spoke about the controversy she found herself in after playing a crystal flute owned by the fourth US president and slave owner James Madison.
Earlier in October, she was accused of condoning Madison's actions by playing the flute onstage.
"When people look back at the crystal flute, they're going to see me playing it," Lizzo said.
"They're going to see that it was owned by James Madison, but they're going to see how far we've had to come for someone like me to be playing it in the nation's capital, and I think that that's a cool thing.
"I don't want to leave history in the hands of people who uphold oppression and racism. My job as someone who has a platform is to reshape history."